Abstract：The measuring equipment of Young’ modulus of soft materials was developed based on indentation test. Finite element method (FEM) was utilized to determine the coefficients between Young’s modulus and indentation profiles. Then the Young’s modulus of elastic samples was calibrated by indentation method. Furthermore, the elastic phantoms were measured by commercialized transient elastography equipment. The agreements of measured elastic parameters and the results by indentation method are to verify the feasibility of elastic quantity’s transferring.
［1］Ophir J, Cespedes I, Ponnekanti H, et al. Elastography: a quantitative method for imaging the elasticity of biological tissues［J］. Ultrason Imaging, 1991, 13: 111-134.
［2］Gennisson J L, Catheline S, Chaffa S, et al. Transient elastography in anisotropic medium: Application to the measurement of slow and fast shearwave speeds in muscles［J］. Journal of the Acoustical Society of America, 2003,114:536-541.
［3］Sandrin L, Fourquet B, Hasquenoph J M, et al. Transient elastography: a new noninvasive method for assessment of hepatic fibrosis［J］. Ultrasound Med Biol, 2003, 29（12）:1705-1713.
［4］Hall T J, Milkowski A, Garra B, et al. RSNA/QIBA: Shear wave speed as a biomarker for liver fibrosis staging［C］//IUS. IEEE International Ultrasonics Symposium, 2013:397-400.
［5］Liu K, Bian X, Fang H, et al. Traceability of elastic parameters in elastography—A feasibility study［C］//BMEI. 2011 4th International Conference on Biomedical Engineering and Informatics, Shanghai, 2011:556-559.
［6］Oudry J, Lynch T, Vappou J, et al. Comparison of four different techniques to evaluate the elastic properties of phantom in elastography: is there a gold standard?［J］. Physics in Medicine and Biology, 2014,59(19): 5775-5793.
［7］黄燕平, 郑永平. 组织弹性测量之传统印压测试［J］. 中国医疗设备, 2011, 26(7):1-12.
［8］Sarvazyan A P, Rudenko O V, Swanson S D, et al. Shear wave elasticity imaging: a new ultrasonic technology of medical diagnostics［J］. Ultrasound in Medicine and Biology, 1998, 24(9):1419-1435.
［9］Egorova V, Tsyuryupaa S, Kaniloa S, et al. Soft tissue elastometer［J］. Medical Engineering & Physics, 2008, 30(2):206-212.
［10］黎正伟, 陶兴付, 树学峰, 等. 纳米压痕仪的压头面积函数校准方法的比较研究［J］. 计量学报, 2015, 36(4): 403-407.
［11］Zerhouni M B, Rachedine M. Ultrasonic calibration material and method: US 5196343［P］. 1993.
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