The Compensation Method of the Supported Bilayer Lipid Membrane Electrode Temperature
LV Ying-chun1,QIN Jian-min2,LV Qing1
1. College of Information Engineering, Taiyuan University of Technology, Taiyuan, Shanxi 030024, China;
2. College of Physics and Optoelectronics, Taiyuan University of Technology, Taiyuan, Shanxi 030024, China
Abstract：An electrode process temperature compensation method of supported bilayer lipid membrane(S-BLM) conductance is proposed.By S-BLM conductance sensor test system, the relationship between S-BLM conductance and temperature is studied.Under the premise of linear hypothesis, using the least square parameter estimation method,the S-BLM conductance sensor's characteristic curve linear equations between slope, intercept and temperatures are derived,then according to characteristics of the sensor curves get S-BLM electrode process temperature compensation model and provide realization method using LabVIEW.Based on effect test of the linear hypothesis and accuracy analysis,and through actual test, the validity and practicability of the proposed method is confirmed.
［1］Becucci L,Innocenti M,Salvietti E,et al.Potassium ion transport by gramicidin and valinomycin across a Ag(1 1 1)-supported tethered bilayer lipid membrane［J］.Electrochimica Acta,2008, 53(22): 6372–6379.
［2］包春燕,贾慧娟,刘涛,等.双分子层膜人工离子通道的合成［J］.化学进展,2012,24(7):1337-1344.
［3］Snatosh Pandey.Analytical modeling of the ion number fluctuations in biological ion channels［J］.Journal of nanoscience and nanotechnology,2012,12(3):2489-2495.
［4］Zhang Y L,Dunlop J, Phung T,et al.Supported bilayer lipid membranes modified with a phosphate ionophore［J］.Biosensors & Bioelectronics,2006,21(12):2311-2314.
［5］Tien H T,Ottova A L.Supported planar lipid bilayers (s-BLMs) as electrochemical biosensors review［J］.Electrochimica Acta, 1998,43(23):3587-3610.
［6］毕只初.微型支撑双层类脂膜pH电极的研制［J］.膜科学与技术,2002,22（5）: 25-28.
［7］刘海,杨慧中.一种智能在线pH检测仪［J］.江南大学学报（自然科学版）,2012,11（2）:173-177.
［8］李代禧,刘宝林,乔勇进,等.温度变化对钾离子跨膜通道蛋白传输能力的影响［J］.计算机与应用化学,2012,29（4）:405-408.
［9］陈为,刘佳,孙长森,等.温度敏感TRP通道作为神经病理痛药物靶点的研究进展［J］.生理科学进展,2012,43（2）:125-129.
［10］吕迎春,马福昌.固体支撑双层类脂膜电极的稳态特性分析［J］.仪表技术与传感器,2011,（6）:8-11.
2013, Vol. 34 
