Method of CRP Rapid Analyzer Based on Formazine Polymer
ZHANG Yi-wen1,ZHAO Xu2, WANG Jun1, WEI Yong-hao1, MA Kang3, WU Hong1,ZHAO Hai-bo1
1. Beijing Institute of Metrology, Beijing 100012, China
2.Tiancun Community Health Service Centers, Beijing 100143, China
3. National Institute of Metrology, Beijing 100029, China
Abstract C-reactive protein (CRP) rapid analyzer is one of the commonly used rapid testing instruments in primary medical institutions. At present, there are no relevant regulations and specifications for traceability and reliability of this type of instrument. By analyzing the molecular size and molecular weight distribution of formazine solution and C-reactive protein solution, the instrument was tested on the basis of scattering principle and referring to the method items of JJG 880—2006 turbidimeter, and the rationality of the method was evaluated. Quikread101 (Rate Scattering) CRP rapid analyzer from Orion manufacturer was used in the experiment. The results showed that the linearity and repeatability of the determination were good when the formazine solution series was tested in turbidity range of (675~1 000) NTU. By comparing a series of formazine solutions with the series of C-reactive protein solutions, the corresponding turbidity values of formazine solutions were found, which provided a reference method for tracing the values of these instruments.
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2021, Vol. 42 
