The Temperature Rise of Tissue-Mimicking Phantom under the Action of High Intensity Focused Ultrasound

CHEN Ning; ZHAO Peng; WANG Yue-bing; CAO Yong-gang

doi:10.3969/j.issn.1000-1158.2021.12.13

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Acta Metrologica Sinica ›› 2021, Vol. 42 ›› Issue (12) : 1635-1642. DOI: 10.3969/j.issn.1000-1158.2021.12.13

The Temperature Rise of Tissue-Mimicking Phantom under the Action of High Intensity Focused Ultrasound

CHEN Ning,ZHAO Peng,WANG Yue-bing,CAO Yong-gang

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Abstract

In order to research the rule of tissue temperature rise under the action of high-intensity focused ultrasound (HIFU), a finite element simulation model of high-intensity focused acoustic field and tissue temperature field is established, and the simulation model is verified by in vitro irradiation experiments. The focused acoustic field in the water and tissue domain is modeled by simulation, and the absorbed acoustic energy is calculated and used as a heat source to calculate the temperature rise within the tissue. By preparing a biological tissue gel phantom, thermocouples are used to measure the temperature at the focal point of the phantom tissue under the action of HIFU. The results show that the model can effectively predict the temperature rise during HIFU treatment, and the difference between the temperature obtained in the experiment is not more than 3℃; the temperature of the phantom tissue will rise immediately when the phantom tissue is irradiated by ultrasound, and the temperature rise rate is faster at first, as the time increases, the temperature rise rate gradually decreases, and the temperature drops immediately after the irradiation is stopped.

Key words

metrology / HIFU / biological tissue model / temperature rise curve / finite element simulation

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CHEN Ning,ZHAO Peng,WANG Yue-bing,CAO Yong-gang. The Temperature Rise of Tissue-Mimicking Phantom under the Action of High Intensity Focused Ultrasound[J]. Acta Metrologica Sinica. 2021, 42(12): 1635-1642 https://doi.org/10.3969/j.issn.1000-1158.2021.12.13

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