仿生物组织模型对高强度聚焦超声焦域影响的研究

doi:10.3969/j.issn.1000-1158.2020.08.14

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Abstract The effect of acoustic characteristics of biological tissue on focal area of HIFU(high intensity focused ultrasound) was analyzed by finite element simulation, which provided theoretical basis for the safety and reliability of HIFU treatment. Ultrasonic propagation equation and frequency-domain finite element method (FEM) were applied to simulate the changes in focal area caused by the characteristics and thickness of tissues during HIFU treatment, and tissue mimicking phantoms were produced to verify the changes in focal area. The influences of characteristics and thickness of tissue on the focus area and location were analyzed and discussed. As a result, with the increase of acoustic velocity, the size of the focal region remained unchanged, and the focal region was closer to the side of the transducer. As the thickness increased, the size of the focal area basically remained unchanged. If acoustic velocity of the tissue was greater than that of the water, the focal area would be closer to the side of the transducer;if acoustic velocity of the tissue was less than that of the water, the focal area would move away from the transducer.

Key words： metrology acoustic characteristics HIFU finite element focal area

Received: 26 November 2019 Published: 13 August 2020

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TB95

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	Articles by authors
	XU Ao-xuan
	WANG Yue-bing
	ZHENG Hui-feng
	CAO Yong-gang

Cite this article:

XU Ao-xuan,WANG Yue-bing,ZHENG Hui-feng, et al. Research on the Influence of Tissue Mimicking Phantomon Focal Area of HIFU[J]. Acta Metrologica Sinica, 2020, 41(8): 975-982.

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http://jlxb.china-csm.org:81/Jwk_jlxb/EN/10.3969/j.issn.1000-1158.2020.08.14 OR http://jlxb.china-csm.org:81/Jwk_jlxb/EN/Y2020/V41/I8/975

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