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| Flow Pulsation Study of HPLC Pumps |
| YANG San-dong1,PAN Qi1,WANG Feng-yun1,HAO Qing-li1,TANG Tao1,2,LI Tong2 |
1. Nanjing University of Science and Technology, Nanjing, Jiangsu 210094, China
2. Dalian Elite Analytical Instruments Co. Ltd., Dalian, Liaoning 116023, China |
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Abstract An innovative system was designed and constructed to measure flow pulsations of reciprocating pumps used in high performance liquid chromatography (HPLC). The flow pulsations of a serial pump and a parallel pump were studied under different conditions. The flow pulsation trends along with the changes of flow rates and backpressures of these two kinds of pumps were acquired. It was confirmed that the flow pulsation cycle was closed to the cam motion cycle. A pulsation damper was applied to reduce the flow pulsations to about 10% under 6.5MPa. This system and method were helpful to design and improve HPLC pumps.
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Received: 25 December 2015
Published: 16 June 2017
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2017, Vol. 38 
