Abstract：To meet the real-time precision measurement requirements of axial compressive force and radial shear force for fracture trauma cross-section, a miniature two-dimensional force sensor based on the E-type round diaphragm structure was designed. The theoretical analysis model for sensor elastomer strain was established. The main structure sizes of sensor elastomer were optimized according to the theoretical analysis model, and the strain gauge position and the combination bridge ways on the elastomer were designed. The calibration experiments for the sensor were carried out to obtain the calibration data. The experimental results show that the sensitivity of the sensor is 2.9 MPa/N, the full scale nonlinear error of axial force is 1.1783%, and the full scale nonlinear error of radial force is 1.0416%.