Abstract：The effect of acoustic characteristics of biological tissue on focal area of HIFU(high intensity focused ultrasound) was analyzed by finite element simulation, which provided theoretical basis for the safety and reliability of HIFU treatment. Ultrasonic propagation equation and frequency-domain finite element method (FEM) were applied to simulate the changes in focal area caused by the characteristics and thickness of tissues during HIFU treatment, and tissue mimicking phantoms were produced to verify the changes in focal area. The influences of characteristics and thickness of tissue on the focus area and location were analyzed and discussed. As a result, with the increase of acoustic velocity, the size of the focal region remained unchanged, and the focal region was closer to the side of the transducer. As the thickness increased, the size of the focal area basically remained unchanged. If acoustic velocity of the tissue was greater than that of the water, the focal area would be closer to the side of the transducer;if acoustic velocity of the tissue was less than that of the water, the focal area would move away from the transducer.
徐遨璇,王月兵,郑慧峰,曹永刚. 仿生物组织模型对高强度聚焦超声焦域影响的研究[J]. 计量学报, 2020, 41(8): 975-982.
XU Ao-xuan,WANG Yue-bing,ZHENG Hui-feng,CAO Yong-gang. Research on the Influence of Tissue Mimicking Phantomon Focal Area of HIFU. Acta Metrologica Sinica, 2020, 41(8): 975-982.
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2020, Vol. 41 
