液闪TDCR方法测量18F核素活度

刘皓然,柳加成,梁珺成,杨元第,袁大庆

计量学报 ›› 2011, Vol. 32 ›› Issue (z1) : 26-29.

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计量学报 ›› 2011, Vol. 32 ›› Issue (z1) : 26-29. DOI: 10.3969/j.issn.1000-1158.2011.z1.07

液闪TDCR方法测量18F核素活度

  • 刘皓然1,柳加成2,梁珺成2,杨元第2,袁大庆1
作者信息 +

Activity Measurement of 18F with TDCR-LS Methods

  • LIU Hao-ran1,LIU Jia-cheng2,LIANG Jun-cheng2,YANG Yuan-di2,YUAN Da-qing1
Author information +
文章历史 +

摘要

18F是重要的医用短半衰期核素,广泛应用于核医学正电子发射断层成像(PET)。18F衰变到18O基态(包括96.86%的β+发射和3.14%的电子俘获EC衰变),考虑到β+衰变分支在液闪中有非常高的探测效率,实验采用液闪TDCR方法绝对测量18F核素活度。测量结果表明,β+衰变分支在Ultima GoldTM AB闪烁液中的探测效率接近1,液闪TDCR方法测量18F的不确定度水平仅为0.62%(k=2)。

Abstract

As an important short half-life radionuclide,the 18F is widely used in nuclear medicine for positron emission tomography(PET).It disintegrates to 18O by β+ emission(96.86%)and electron capture(3.14%).Since the very high detection efficiency of β+ decay branch in the liquid scintillation counter,the radioactive solution of 18F has been standardized by TDCR-LS method.The results indicate that the detection efficiency of β+ emission in Ultima GoldTM AB cocktail is close to 1 and the uncertainty of 18F by TDCR-LS method is equal to 0.6%(k=2).

关键词

计量学 / 18F / 液闪TDCR方法 / 活度

Key words

Metrology / 18F / TDCR-LS methods / Radioactive

引用本文

导出引用
刘皓然,柳加成,梁珺成,杨元第,袁大庆. 液闪TDCR方法测量18F核素活度[J]. 计量学报. 2011, 32(z1): 26-29 https://doi.org/10.3969/j.issn.1000-1158.2011.z1.07
LIU Hao-ran,LIU Jia-cheng,LIANG Jun-cheng,YANG Yuan-di,YUAN Da-qing. Activity Measurement of 18F with TDCR-LS Methods[J]. Acta Metrologica Sinica. 2011, 32(z1): 26-29 https://doi.org/10.3969/j.issn.1000-1158.2011.z1.07
中图分类号: TB98   

参考文献

[1]DDEP-Decay Data Evaluation Project[DB],http://www.nucleide.org/DDEP_WG/Nuclides/F-18_tables.
[2]Broda R,Pochwalski K.The enhanced triple to double coincidence ratio(ETDCR)method for standardization of radio-nuclides by liquid scintillation counting[J].Nucl Instrum Methods,1992,A312:85-89.
[3]Broda R,Cassette P,Kossert K.Radionuclide metrology using liquid scintillation counting[J].Metrologia,2007,44:36-52.
[4]Grau Carles A.New Methods for the Determination of beta Spectra Shapefactor Coefficients[J],Appl Radiat Isot,1995,46(2):125-128.
[5]Birks J B.The Theory and Practice of Scintillation Counting[M],London:Pergamon Press,1960,186-187.
[6]吴永乐,液闪TDCR方法测量氚水活度[D].北京:中国原子能科学研究院, 2010.
[7]Broda R,Maletka K,et al.Study of the influence of the LS-cocktail composition for the standardization of radionuclides using the TDCR mode1[J].Appl Radiat Isot,2002,56:285-289.
[8]Miguel R,Eduardo G T,Leonor R B.Standardization of 18F by coincidence and LSC methods[J].Appl Radiat Isot,2006,64:1192-1202.
[9]梁珺成,应用CIEMAT/NIST方法测量轨道电子俘获核素活度的研究[D].北京:中国计量科学研究院,2008.
[10]Bouchard J,Cassette P.MAC3:an electronic module for the processing of pulses delivered by a three photomultiplier liquid scintillation counting system[J].Appl.Radiat.Isot.2000,52:669-672.

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